http://journalijmpcr.com/index.php/IJMPCR/issue/feed International Journal of Medical and Pharmaceutical Case Reports 2019-11-12T08:59:52+00:00 International Journal of Advances in Nephrology Research contact@journalijmpcr.com Open Journal Systems <p style="text-align: justify;"><strong>International Journal of Medical and Pharmaceutical Case Reports (IJMPCR) (ISSN: 2394-109X)</strong> aims to publish case reports in the areas of medical and pharmaceutical sciences.&nbsp;The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.&nbsp;</p> http://journalijmpcr.com/index.php/IJMPCR/article/view/30105 Detection of Metastatic Breast Carcinoma Cells in Bone Marrow by Flow Cytometry 2019-11-12T08:59:52+00:00 Manoela Lira Reis Daniella Serafin Couto Vieira Laura Otto Walter Maria Claudia Santos-Silva santosdasilvamc@gmail.com <p>Breast cancer is the most common cause of cancer death in women worldwide. Cytological, histological, and immunohistochemical techniques are routine laboratory tests for determining tumor subtypes. Over the past few years, laboratory diagnostic tests for breast cancer have become more complex, sophisticated, and specialized. This report describes the case of a young patient with metastatic breast cancer whose diagnosis was based on flow cytometric analysis of bone marrow aspirate. Flow cytometry showed to be an important tool in cancer diagnosis. Its application as a routine laboratory test for the diagnosis of solid tumors, such as breast cancer, can help provide fast results while increasing diagnostic coverage.</p> 2019-09-09T00:00:00+00:00 ##submission.copyrightStatement## http://journalijmpcr.com/index.php/IJMPCR/article/view/30106 Vocal Folds: An Unusual Hideout for Systemic Sarcoidosis 2019-11-12T08:59:51+00:00 Anis Hariz anis_hariz@yahoo.fr Abir Derbel Ines Kechaou Imène Boukhris Mohamed Salah Hamdi Eya Cherif <p>Sarcoidosis is a chronic inflammatory granulomatous disease of unknown etiology. It can expand to all organs and tissues. Lungs and lymph nodes are the most commonly involved tissues. Laryngeal sarcoidosis is rare, accounting for no more than 1% of patients with systemic sarcoidosis. We herein report the case of a 51-year-old female presenting a two-year history of persistent voice hoarseness with direct laryngoscopy findings of epiglottis swelling and irregular swelled and bruised left vocal fold. Histological examination highlighted the presence of non-caseating granulomas. Further investigations revealed similar histological findings in the nasal cavity as well as lymphocytic alveolitis. It also showed the presence of phalangeal bone lesions of both hands. All these pointed to the diagnosis of sarcoidosis with upper respiratory tract (nasal and laryngeal), lung and bone involvement. The patient was started on 0.5 mg/kg daily of prednisone for 1 month followed by progressive tapering with lasting favorable outcome.</p> 2019-11-04T00:00:00+00:00 ##submission.copyrightStatement##