Through Indian Eyes: A Case Series on Steroid-induced Secondary Cataract
B S Girish *
Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences (Formerly PES College of Pharmacy), PES University, Electronic City, Bengaluru, Karnataka, 560100, India.
C S Meghana
Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences (Formerly PES College of Pharmacy), PES University, Electronic City, Bengaluru, Karnataka, 560100, India.
Joel M. Johns
Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences (Formerly PES College of Pharmacy), PES University, Electronic City, Bengaluru, Karnataka, 560100, India.
R. Srinivasan
Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences (Formerly PES College of Pharmacy), PES University, Electronic City, Bengaluru, Karnataka, 560100, India.
*Author to whom correspondence should be addressed.
Abstract
Lichen planus, a chronic autoimmune dermatological disorder, often necessitates the use of topical corticosteroids for symptom management. However, this case series highlights the emergence of topical steroid-induced secondary cataracts in two patients, emphasizing a previously underrecognized complication. Both patients, females aged 36 and 43, presented with gradual vision loss in their left eyes, attributed to prolonged corticosteroid use for lichen planus and skin allergies, respectively. Ophthalmological examinations confirmed the diagnosis, leading to cataract surgeries. The pathogenesis involves complex cellular and molecular mechanisms, emphasizing the need for vigilant monitoring during corticosteroid therapy. Moreover, the lack of stringent reporting systems for adverse drug reactions in India underscores the necessity for comprehensive monitoring to mitigate economic and quality of life burdens. The study emphasizes the importance of judicious corticosteroid use, tapering regimens, and patient education to minimize complications while effectively managing dermatological conditions. This underscores the critical need for heightened awareness, surveillance, and patient-centred approaches to mitigate the risk of corticosteroid-induced secondary cataracts, ensuring optimal therapeutic outcomes and long-term ocular health.
Keywords: Steroid-Induced, cataract, corticosteroids, corticosteroid therapy, cataract formation
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References
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