Open Access Case Study

Spontaneous Closure of Patent Ductus Arteriosus in an Adult Patient: A Case Report

Silanath Terpenning, Cheng Ting Lin, Charles S. White

International Journal of Medical and Pharmaceutical Case Reports, Page 53-56
DOI: 10.9734/IJMPCR/2015/12786

Patent Ductus Arteriosus (PDA) is a well-described congenital heart disease in infants and children but is less commonly reported in adults. Mechanical, surgical and spontaneous closure of PDAs in infants and fetuses are common, however spontaneous closure of PDA in adults is uncommon and has not been reported in the recent literature. We present a case report of spontaneous closure of a PDA in a 49 years old patient demonstrated on cardiac computed tomography (CT).

Open Access Case Study

Successful Treatment with Dapsone for Refractory Immune Thrombocytopenia

Yasuhiro Maeda, Kenta Yamamoto, Ayano Fukui, Go Eguchi, Terufumi Yamaguchi

International Journal of Medical and Pharmaceutical Case Reports, Page 57-60
DOI: 10.9734/IJMPCR/2015/13139

In adult with immune thrombocytopenia (ITP), it has been known that steroids have been used as a first-line therapy. The therapy induced remission in more than 60% of patients. Here, we evaluated the results of dapsone for a steroid-resistant ITP patient. Further, dapsone has been reported to emerge as a safe and inexpensive therapy for chronic ITP. In this case, we showed a relationship between platelet count and grade of hemolysis by treatment with dapsone.

Open Access Case Study

Excessive Thumb Motion Causing Delayed Tendon Injury to Wrist First Extensor Compartment Associated with Flexible Nail

Bisher Alshanawani, Abdulmonem Mohammed Alsiddiky, Feras Alshomer, Mohamed Zamzam

International Journal of Medical and Pharmaceutical Case Reports, Page 61-65
DOI: 10.9734/IJMPCR/2015/13583

Aim: To withdraw the attention to the possible complication of tendons rupture in cases of intramedullary flexible nail fixating cases of pediatric both bone forearm fractures.
Presentation of Case: A 16 years old boy with a history of right forearm both bones mid shaft fracture was managed with closed reduction and flexible intra-medullary nail fixation. The patient was doing fine but, four months later he sustained sharp pain that was associated with limitation of thumb motions while using a video game controller. Surgical exploration revealed rupture of Extensor Polices Brevis (EPB) and attrition of Abductor Pollicis Longus (APL) tendons by rubbing over the free bent end of the flexible nail. This complication was managed satisfactorily.
Discussion: The authors are reporting this case for the treating physicians to be aware about such complication, which should be avoided. Elaborating for the first time a presumed causal association between daily thumb motion and risk of injury that should be kept in mind while treating such cases to prevent possible complication.
Conclusion: Treating mid-shaft radial fracture in children with flexible nails is subjected to this possible complication. The free end of the flexible nail must be away from the excursion of any of wrist tendons. Changes in lifestyle habits that result in excessive motion of the involved joint should be avoided. A multidisciplinary team approach is essential in the management plan.

Open Access Case Study

An Unusual Case of Acute Myopericarditis Possibly Due to Food Poisoning

Annapaola Zito, Fiorella Devito, Annamaria Dachille, Rosa Carbonara, Francesco Giardinelli, Ottavio Di Cillo, Marco Matteo Ciccone

International Journal of Medical and Pharmaceutical Case Reports, Page 66-69
DOI: 10.9734/IJMPCR/2015/12942

The manuscript describes the case of a 23 year-old woman, with acute myopericarditis associated with food poisoning without other cardiovascular disease. The patient had a history of hypothyroidism, treated with levothyroxine 75 μg/d, however she was clinically and biochemically euthyroid. We present a discussion of this rare association, followed by clinical presentation and treatment. This case report underlines the importance of considering possible cardiac complications when treating patients with food poisoning.

Open Access Case Study

Papillary Glioneuronal Tumor: A Case Report and a Brief Review

Amir Hossein Jafarian, Nema Mohammadian Roshan, Abbas Ali Omidi, Samaneh Boroumand-Noughabi

International Journal of Medical and Pharmaceutical Case Reports, Page 70-75
DOI: 10.9734/IJMPCR/2015/13550

Aims: Papillary glioneuronal Tumor (PGNT) is a rare, recently recognized glioneuronal tumor. To date only about 68 cases of PGNT have been reported. Although it has been regarded as a grade 1 neuronal – glial tumor by World Health Organization, aggressive cases have been reported and so, they can be challenging to diagnose and to treat as their relatively unclear clinical course. In this article, we summarize the clinical and pathological findings of this new entity.
Presentation of Case: The patient was a 23-year-old man with headaches and right hemiparesis who had a tumor arising in close proximity of the anterior horn of the left lateral ventricle. No mitotic activity was identified, confirmed by Ki-67 labeling of about 1%. There was no evidence of recurrence during 64 month follow-up. A brief review of the other reported cases also has been included.
Discussion and Conclusion: Although PGNT has been regarded as a grade 1 tumor, aggressive cases have been reported and their behavior has not been related to histological grading. So, all cases need to be reported to make further knowledge about its biological behavior.