Open Access Clinical Practice Article

Tridax procumbens Effects on Lesions, Haematology and Eggs Production of Hens Affected by Fowlpox

T. M. Kpodekon, T. J. Dougnon, J. S. E. Goussanou, C. Boko

International Journal of Medical and Pharmaceutical Case Reports, Page 1-9
DOI: 10.9734/IJMPCR/2015/18910

The powder of Tridax procumbens was added to hens’ food to assess its effects on fowlpox lesions, hematological parameters and zootechnic parameters. Five batches of ten hens each were installed either in control or in treatment groups. The powder of Tridax procumbens was added to hens’ food using various proportions and different experimental periods. The scabs disappeared on the crests and on wattle of hens fed with Tridax procumbens. The number of red blood cells, haemoglobin content (Hb), average contents in haematocrit (Ht), average corpuscular concentration in haemoglobin (ACCH) and average corpuscular content in haemoglobin (ACCtH) increased while the number of leukocytes decreased. Compared to the control batch, the laying rate increased in the four experimental batches during the first 28 experimental days, when the conversion index decreased.

Open Access Case Study

Utility of Diffusion-Weighted Magnetic Resonance Imaging for Predicting a Prognosis in Hypoglycemic Encephalopathy: Two Case Reports

Syuichi Tetsuka, Asako Tagawa, Tomoko Ogawa, Mieko Otsuka, Ritsuo Hashimoto, Hiroyuki Kato

International Journal of Medical and Pharmaceutical Case Reports, Page 1-6
DOI: 10.9734/IJMPCR/2015/19534


Case 1: A 71-year-old male with a long history of chronic alcoholism was transferred to our emergency department because of a disturbance of consciousness. On arrival, his Glasgow Coma Scale (GCS) was E1V1M2 (4/15) and blood glucose level was 30 mg/dL.

Case 2: A 66-year-old female with dermatomyositis and a long history of steroid-induced diabetes mellitus, who was treated with a sulfonylurea, was transferred to our department because of an altered mental state. Her GCS was E3V2M4 (9/15) and blood glucose level was 32 mg/dL. We observed abnormalities on diffusion-weighted magnetic resonance images (DWI-MRI) in both cases.

Outcomes: Although intravenous thiamine and glucose was immediately administered because of suspected hypoglycemic encephalopathy, case 1 died after 3 days, and case 2 remained in a persistent vegetative state more than 90 days after onset.

Conclusion: Unlike conventional MRI, DWI-MRI abnormalities can be used as predictors of poor prognosis in patients with severe hypoglycemia.

Open Access Case Study

Congenital Unilateral Chylothorax in a Non-immune Hydropic Newborn with Down Syndrome

Baran Serdar Kizilyildiz, Kamuran Karaman, Bülent Sönmez, Burhan Beger

International Journal of Medical and Pharmaceutical Case Reports, Page 1-5
DOI: 10.9734/IJMPCR/2015/19624

Chylothorax is defined as accumulation of lymph within the pleural space. It is the most common cause of pleural effusion causing respiratory distress in the first few days of life. Congenital chylothorax and Down syndrome are independently have been found in association with non-immune hydrops fetalis. On the other hand, these entities can seen together. The treatment of congenital chylothorax generally based on cessation of enteral feeding, initiation of total parenteral nutrition and introduction of medium chain triglycerides. Surgical intervention should be encountered when medical therapy fails. We present a hydropic newborn with Down syndrome and chylothorax who was successfully treated by chest drainage and conservative treatment.

Open Access Case Study

H1N1 Vaccine May Cause Hepatic Dysfunction

Ferdane Sapmaz, Sebahat Başyiğit

International Journal of Medical and Pharmaceutical Case Reports, Page 1-3
DOI: 10.9734/IJMPCR/2015/18807

Aim: In this case, we reported an unusual side effect which may be related to adjuvant H1N1 vaccine.

Case Report: A sixty-three year-old man was admitted to our hospital with fever, nausea, vomiting and fatigue 15 days after his immunization against H1N1 virus. Laboratory findings were, aspartate aminotransferase (AST):620 U/L, alanine aminotransferase (ALT): 561 U/L, alkaline phosphatase (ALP):152 U/L, gamma-glutamyl transferase (GGT): 482 U/L. His clinical symptoms resolved within two days. His elevated liver function tests reduced gradually and completely normalized on day 6 of his hospitalization.

Discussion and Conclusion: H1N1 vaccination may cause increases in liver enzymes and it should be considered in differential diagnosis of abnormal liver function tests.

Open Access Case Study

Cartap Hydrochloride Poisoning Causing Respiratory Failure and Seizures

Mahesh Babu Sodalagunta, Sreenivasa Rao Sudulagunta, Hadi Khorram, Mona Sepehrar

International Journal of Medical and Pharmaceutical Case Reports, Page 1-4
DOI: 10.9734/IJMPCR/2015/19466

Cartap hydrochloride is a commonly used low toxicity insecticide. It is a thiocarbamate with the chemical formula C7H16ClN3O2S2 and a nereistoxin analogue. Major formulations available in India are cartap hydrochloride 4% GR (granules) and cartap hydrochloride 50% SP (soluble powder). We report regarding a 30 year old male patient who presented to the emergency department with alleged history of ingestion of large amount of cartap hydrochloride along with alcohol with intention of suicide. Patient developed hiccups, nausea, vomiting, dyspnea and 2 episodes of generalized tonic clonic seizures. Patient required mechanical ventilation for a period of 5 days and infusion of N-acetyl cysteine. 

Toxic effect of Cartap hydrochloride is predominantly through dose-dependent inhibition of  [(3)H]-ryanodine binding to Ca2+ release channel in the sarcoplasmic reticulum and promotion of Ca2+ influx outside the cells and induction of Ca2+ release inside the cells. This is the basis of clinical features of acute poisoning and treatment with British Anti Lewisite and sodium dimercaptopropane sulfonate.