Open Access Case Study

Paraneoplastic Nephrotic Syndrome in Breast Cancer HCV Positive- A Case Report

Georgescu Aristida, Irimia Ionela, Barbulescu Diana, Stoican Decebal

International Journal of Medical and Pharmaceutical Case Reports, Page 1-8
DOI: 10.9734/IJMPCR/2016/23885

Aims: Our aim was to illustrate a case of Membranous Glomerulopathy (MG), which is the commonest paraneoplastic pathology associated with the nephrotic syndrome, and develops in parallel with salient/ unapparent cancer evolution phases.

Presentation of Case: We present a rare case of a 39-year-old female patient with nephrotic syndrome considered secondary to a Hepatitis C with elevated viremia and to a breast cancer (BC), which was lately revealed by Ductal Echography (DE) and confirmed by Mammography and fine-needle aspiration biopsy, with BC staged T4NxMx.

Discussion: The nephrotic syndrome is usually considered as idiopathic, at least in the initial stage. Some other diseases may be incriminated as etiological factors in the secondary nephrotic syndrome, with simultaneous evolution and improvement/healing of the nephrotic impairment after the removing of the associated disease.

Conclusion: The paraneoplastic nephrotic syndrome associated to BC is a rare condition, and the best cost-efficient method of diagnosis could be the anatomical technique of Ultrasonography / DE, which is not operator dependent and allows the accurate detection of breast malignancy, suitable in earlier stages. Otherwise, some cases are missed or diagnosed in advanced stages, such in this presentation.

Open Access Case Study

Osteitis Fibrosa Cystica of Jaws as Diagnostic Criteria for Hyperparathyroidism – A Case Report with Review of Literature

S. N. Santhosh Kumar, Kalyani Bhate, Vivek Pawar, Kapil Kshirsagar, Vijay Gupta, Sushmita Mitra, Suraj Bangar

International Journal of Medical and Pharmaceutical Case Reports, Page 1-6
DOI: 10.9734/IJMPCR/2016/24344

Maxillo-mandibular swellings are one the common presentations with which, patient approach a surgeon. These maxillo-mandibular swellings may be reactionary, benign, malignant and sometimes secondary to some underlying systemic disorders. There is a necessity for the surgeons to deviate from the traditional surgical management for those maxillo-mandibular swellings secondary to underlying systemic disorders. Here is a case report of 46-year old female who complained of swelling in the right maxilla and left mandible secondary to brown tumour, with an emphasis on the protocol for the management.

Open Access Case Study

Samter’s Triad: Rare or Under-Diagnosed?

Adekunle Olatayo Adeoti, Oluwatoba Ezekiel Osasona, Olatunji Bukola Olaoye, Olufemi O. Desalu

International Journal of Medical and Pharmaceutical Case Reports, Page 1-5
DOI: 10.9734/IJMPCR/2016/24677

Samter’s triad is an acquired inflammatory disorder characterized by asthma, nasal polyps and aspirin sensitivity. Aspirin sensitivity is the hallmark of this condition. It is a form of pseudo-allergy, as IgE does not play any significant role in its pathophysiology. There is a paucity of reported cases of Samter’s triad in Africa.

Our patient is a 24-year old female who presented with worsening of asthmatic symptoms and naso-ocular complaints after thirty minutes of intake of non-steroidal anti-inflammatory drugs (NSAIDs) for dysmenorrhea. We found bilateral nasal polyps on examination of her nostrils and two previous episodes of similar reactions to NSAIDs.

There is a need for increased awareness about this condition among healthcare givers managing patients with bronchial asthma as several cases may be missed in hospital settings. Samter’s triad requires detailed drug history of sensitivity to NSAIDs with accompanying naso-ocular manifestations in all asthmatic patients.

Open Access Case Study

Role of Interpositional Dermal Graft in Management of Recurrent Temporomandibular Joint Ankylosis: A Case Series of Three Patients

Sushmita Mitra, Sagar Joshi, Kalyani Bhate, S. N. Santhosh Kumar, Kapil Kshirsagar, Vivek Pawar

International Journal of Medical and Pharmaceutical Case Reports, Page 1-5
DOI: 10.9734/IJMPCR/2016/24486

The Temporomandibular joint (TMJ) ankylosis is a condition of the joint that causes problem in mouth opening, mastication, digestion, speech, hygiene and appearance. The treatment of TMJ ankylosis poses a significant challenge because of high incidence of recurrence and technical difficulties. Various soft tissue grafts like temporalis fascia and temporalis muscle, collagen membrane and dermal fat pad have been used in the surgical management of TMJ ankylosis. We present a series of three recurrent cases of TMJ ankylosis in which we used dermal fat graft as interpositional graft.

Open Access Case Study

Paradoxical Lymphadenopathy after Successful Treatment of Tuberculous Pleuritis

Esfandiar Shojaei, Mehrnaz Rasoolinejad, Saeed Kalantari

International Journal of Medical and Pharmaceutical Case Reports, Page 1-4
DOI: 10.9734/IJMPCR/2016/24319

Tuberculous lymphadenopathy can paradoxically increase in size after initial clinical improvement. This paradoxical reaction during tuberculosis treatment is more common among HIV positive than non-HIV patients. However paradoxical reaction must not be primary diagnosis and it is crucial to be sure about patientsˋ good compliance in using antituberculosis medications as well as having sensitive mycobacterial strain. In addition other pathological problems (eg. neoplasia, other non tuberculous mycobacterial infections) should be excluded. We report a case of pleural tuberculosis, complicated by cervical lymphadenopathy near the end of her treatment.