Open Access Case Report

Hidradenitis Suppurativa: Two-case Reports

Khalifa Y. Hassan

International Journal of Medical and Pharmaceutical Case Reports, Page 1-6
DOI: 10.9734/IJMPCR/2016/25006

Hidradenitis suppurativa (HS) is a common (though rarely diagnosed) disease affecting the apocrine glands. It is chronic in nature and mainly found in areas rich in apocrine glands like axillae, groins, under the breast, buttocks and the gluteal region. The main features of HS are multiple abscesses, sinus tracts, wet oozing lesions and secondary infections. The disease is chronic in nature and negatively affects the quality of life of patients.

HS disorder should be put in mind when a patient has intertrigenous lesions. It could be differential diagnosis, along with the fungal, viral and other bacterial infections.

Open Access Case Study

Treatment of Impacted Maxillary Central Incisor with Removable Appliance: A Case Report

Elham Mohammad-Rabei, Alireza Shamsi, Mohammad Farahani

International Journal of Medical and Pharmaceutical Case Reports, Page 1-6
DOI: 10.9734/IJMPCR/2016/28943

Maxillary central incisors impaction is a challenging problem in orthodontics, which has a major effect on dental and facial esthetics. Scientific literature agree on the importance of early diagnosis and appropriate intervention. This is a case report of a 10 year­old boy who presented with impaction of maxillary central incisor related to previous trauma to primary dentition and apparent space loss. The treatment proposed involved space reopening with removable appliance, a wait­and­watch approach, surgical exposure of impacted tooth followed by orthodontic traction with a removable appliance. This approach showed many advantages over fixed treatment and early exposure in mixed dentition.

Open Access Case Study

Symptomatic Celiac Artery Aneurysm Managed with Celiac Plexus Ablation

Shiwei Huang, Muhammad Azharuddin, Prudence Kho Dy, Wael Ghali, Faisal Naseer

International Journal of Medical and Pharmaceutical Case Reports, Page 1-6
DOI: 10.9734/IJMPCR/2016/29821

A 57-year-old male presented to the ED complaining of severe abdominal pain. Further investigations ruled out gastritis and gastroparesis. Computed tomography (CT) angiography of the abdomen revealed a dissecting aneurysm with a maximum diameter of 1.5 cm at the celiac trunk extending into proximal splenic artery with mural thrombosis. Due to the patient’s medical history, surgical or endovascular repair of the aneurysm carried too much risk. The patient was discharged to home, and symptoms were managed with pain management and celiac plexus ablation as an adjunct to pain medications.

Open Access Case Study

Bactrim-induced Severe Thrombocytopenia in Pregnancy

Shiwei Huang, Robert Tenney, Muhammad Azharuddin, Mridul Gupta, Wael Ghali

International Journal of Medical and Pharmaceutical Case Reports, Page 1-4
DOI: 10.9734/IJMPCR/2016/30229

A 29-year-old Caucasian woman at 30 weeks’ gestation presented with severe and asymptomatic thrombocytopenia with a platelet count of 17 × 109/L after completing 9 days out of a 10-day course of Bactrim DS for a nasal abscess. Upon further investigation, Bactrim-induced thrombocytopenia was diagnosed. After discontinuing this medication, her laboratory abnormalities immediately improved without any additional interventions.

Open Access Case Study

Linezolid Therapy – A Cause of Bone Marrow Suppression in a Child

Vanny Arora, Anju Aggarwal, Sonali Verma, Manish Narang

International Journal of Medical and Pharmaceutical Case Reports, Page 1-4
DOI: 10.9734/IJMPCR/2016/30081

Aim: To highlight the importance of monitoring rare side effects of commonly used drugs. Linezolid induced bone marrow (BM) suppression is rare side effect of therapy and rarely reported in the pediatrics age group.

Case Description: A seven year old patient, with persistent discharge from skull suture site following surgery, developed bone marrow suppression 28 days following the start of treatment with Linezolid. BM suppression was fully reversible following discontinuation of Linezolid and all cell lines returned to near baseline 2 weeks after the discontinuation of the drug.

Discussion: The potent activity of Linezolid against Gram-positive bacteria, and its excellent bioavailability after oral dosing, have made it an important addition to the antibiotic armamentarium. Linezolid is relatively a safer drug and BM suppression is a rarely reported side effect, which is particularly observed when the drug is administered for more than 14 days. 

Conclusion: Case highlights the importance of weekly monitoring of complete blood counts in patients who receive Linezolid for more than 14 days.