Open Access Case Report

Elephantiasis Gingivae – A Case Report and Its Management

P. Venkatalakshmi Aparna, S. Leena Sankari, A. Priyadharshini, M. Kasthuri

International Journal of Medical and Pharmaceutical Case Reports, Page 1-5
DOI: 10.9734/IJMPCR/2018/40157

Gingival fibromatosis is a rare, benign, slowly growing heterogeneous group of disorders that develop local or diffuse enlargements of interdental papilla or attached gingiva and marginal gingiva. In advanced cases, the growth of the tissue may cover the occlusal surface of the teeth, thus causing functional, aesthetic, and periodontal problems, such as bone loss and bleeding, due to the accumulation of plaque and the presence of pseudo pockets. It affects both sexes equally. This condition is usually transmitted as a genetic syndrome and rarely, an isolated condition. Here, we discuss the case on gingival fibromatosis along with a brief description of some characters on clinical, etiological, genetic and histopathological aspects.

Open Access Case Study

The Management of Amlodipine-induced Gingival Overgrowth Associated to Generalized Chronic Periodontitis- A Case Report

Guarnieri Renzo, Di Nardo Dario, Gaimari Gianfranco, Miccoli Gabriele, Testarelli Luca

International Journal of Medical and Pharmaceutical Case Reports, Page 1-9
DOI: 10.9734/IJMPCR/2018/40060

This case report describes the management of an 60 years-old female who presented with generalized chronic periodontitis associated with amlodipine-induced gingival overgrowth. The clinical examination showed generalized edematous gingival tissues, with gingival overgrowth, and presence of bacterial plaque and calculus on the surfaces of the teeth. Patient was a known hypertensive, and she was on medication with amlodipine from past three years. Diagnosis was determined based on history, clinical findings and radiographic examination. With the consent of physician for substitution of amlodipine, treatment consisted of meticulous oral hygiene instruction, scaling, root surface instrumentation, prophylaxis, and daily chlorhexidine mouth rinses. After this stage, periodontal surgery for pockets and excess gingival tissues elimination was performed. The patient has been enrolled in a supportive periodontal maintenance program, and after 3-years, there has been no recurrence.

Open Access Case Study

Multiple Myeloma Presenting in Unusual Extramedullary Sites in a 62 Year Old Female from Kigali, Rwanda: Case Report

Etienne Amendezo, Patrick Kavabushi, Theoneste Nizeyimana, Issa Ngabonziza, Patrick Niyongabo, Kingsley Tobi, Julienne Imuragire, Jean Jacques Nshizirungu, Lynnette Kyokunda-Tumwine

International Journal of Medical and Pharmaceutical Case Reports, Page 1-8
DOI: 10.9734/IJMPCR/2018/39476

Introduction: Multiple myeloma (MM) is a malignant hematological tumor that mainly manifests as osseous lesions in the bone marrow and skeletal bones. It rarely presents in extramedullary sites. Patients with extramedullary disease have been noted to have advanced stage disease with poor prognosis. We describe the clinical, radiological and pathological manifestations of a 62 year old Rwandan female who presented with extramedullary plasmacytoma involving multiple sites including the pleura, pancreas and gall bladder.

Case Presentation: A 62 year old Rwandan female presented with a three week history of intractable post-prandial vomiting, nausea, progressive weight loss, generalized body pain and limb weakness. Our diagnostic work-up showed soft tissue tumors involving multiple organs particularly pleura, pancreas and gall bladder along with diffuse lytic bone lesions in the ribs, spine and pelvis. Laboratory tests showed increased serum amylase, lipase, calcium, lactate dehydrogenase and CA125. Histopathology of the core biopsy of the pleura showed infiltration of monotonous atypical plasma cells. A diagnosis of MM with multiple extramedullary lesions was made. The patient initially improved and reached a partial response on bortezomib, dexamethasone and lenalidomide. However, five months after the initial diagnosis, she died from complications of the disease.

Conclusion: MM may be challenging to diagnose when it presents in unusual sites as extramedullary plasmacytomas.

Open Access Case Study

Venomous Snake Bite in Children: A Case Report from Nigeria

Blessing I. Abhulimhen-Iyoha, Chinwe Oguejiofor, Ejiro Ogonor

International Journal of Medical and Pharmaceutical Case Reports, Page 1-7
DOI: 10.9734/IJMPCR/2018/40082

Venomous snakebite is a commonly encountered pediatric emergency especially in regions of slums, villages, and forests. It presents with varying clinical features leading to morbidity and mortality. Children are more prone to complications as a result of their physiological vulnerability. Mortality is also higher in them because the amount of toxin absorbed per kilogram body weight is more amongst the children than in adults. We report a case of a 7-year-old girl in Benin City, Nigeria who was managed for Disseminated Intravascular Coagulopathy (DIC), necrotizing fasciitis and compartment syndrome following a snakebite. She required blood transfusion for the DIC, fasciotomy for compartment syndrome and skin grafting for the extensive ulcers which are all features of severe envenomation. We conclude that accurate diagnosis and prompt management of complications can save life.

Open Access Case Study

Epiploic Appendix of the Sigmoid Colon Incarcerated in the Right Femoral Hernial Sac – Case Report

Jurij Janež

International Journal of Medical and Pharmaceutical Case Reports, Page 1-3
DOI: 10.9734/IJMPCR/2018/40605

Femoral hernias are more common in female patients and are prone to incarceration. Incarceration of the colonic appendix epiploicae within the femoral hernia sac is a rare finding and is usually diagnosed during emergency surgery. This paper presents a case of an older female patient with incarcerated sigmoid colon appendix epiploicae within the femoral hernia sac.