Open Access Case Report

New Ray of Hope in Prognosis-Significance of Clinical, Histopathological and Biological Characteristics among Potentially Malignant Disorders and Oral Cancer– Case Series

G. Sathees Chandramouli, CH. Uma Reddy, A. Steffina Lydia Jascinth, M. Anitha, B. R. Sathvikalakshmi

International Journal of Medical and Pharmaceutical Case Reports, Page 1-7
DOI: 10.9734/IJMPCR/2018/39111

Early detection of disease progression remains a challenging task mainly due to the lack of adequate early predictive markers. It is necessary to consider the biological behaviour and underlined molecular events while selecting treatment modalities in order to get the better outcome of oral potentially malignant disorders (OPMD) and oral cancer. The aim of the study was to evaluate Cytokeratin (CK) and vimentin expression in pre and post-treatment status of Oral leukoplakia, Oral sub mucous fibrosis (OSMF), Oral squamous cell carcinoma (OSCC) using Immunohistochemistry (IHC). These markers serve as prognostic indicators.

Open Access Case Report

Dermoscopy in the Evaluation of Amelanotic Skin: Two Case Reports on Its Use in the Nigerian Albino

C. R. Madubuko, E. P. Kubeyinje

International Journal of Medical and Pharmaceutical Case Reports, Page 1-6
DOI: 10.9734/IJMPCR/2018/42710

Dermoscopy has been widely used for evaluation of pigmented lesions and the benefits of its use have been enormous especially in the early detection of melanoma. Its efficacy in the evaluation of the albino skin is also worthy of recognition. We report two cases of persons living with albinism where the dermoscopy was very useful. The first was a 35 yr old clergy man with oculocutaneous albinism, who presented with a plaque on the temporal aspect of the face. Dermoscopy showed adherent scales in keeping with actinic keratosis. The second patient was a 25 yr old carpenter presenting with hyperpigmented macular eruptions involving both upper extremities, upper back and neck. Lesions had been present for 10 years. Dermoscopy revealed moth-eaten edges and finger print cords suggestive of solar lentigines.

Open Access Case Study

Intra Bony Epidermoid Cyst Mimicking Odontogenic Cyst – A Case Report

Potluri Venkatalakshmi Aparna, S. Leena Sankari, F. Massillamani, A. Priyadharshini, D. K. S. Lakshminrusimhan

International Journal of Medical and Pharmaceutical Case Reports, Page 1-5
DOI: 10.9734/IJMPCR/2018/20712

Epidermoid and Dermoid cysts are benign lesions encountered throughout the body. These cysts are cystic malformations lined with squamous epithelium. Development of these cysts in the oral cavity is extremely rare. Epidermoid cysts can arise by a development of entrapped ectodermal tissue of the first and second branchial arches or can also arise due to surgical or accidental implantation of epithelial cells into deeper tissues. Clinically, the lesion presents as a slow-growing asymp­tomatic mass, usually located in the midline, above or below the mylohyoid muscle. Histologically, they can be further classified as epidermoid, dermoid or teratoid. Originally the implantation cysts are developed from congenital inclusion of ectodermal tissue during embryological development. But sometimes they may originate through implantation of epithelium by either surgical or accidental trauma into deeper mesenchymal tissues. This article presents a rare case of inclusion type of epidermoid cyst in the body of the mandible.

Open Access Case Study

Early Small Bowel Obstruction in a 9-Year Old Boy After Laparoscopy and Minilaparotomy Due to Traumatic Small Bowel Perforation

Jurij Janež

International Journal of Medical and Pharmaceutical Case Reports, Page 1-4
DOI: 10.9734/IJMPCR/2018/41415

Intra-abdominal adhesions are common after abdominal surgery. They occur more frequently after conventional laparotomy, but they can also occur after laparoscopy and can cause mechanical small bowel obstruction. The reported incidence of adhesive small bowel obstruction in children depends on the type of surgery, but it is estimated to be in 1-6% of children following abdominal surgery.

This paper presented a case of a 9-year-old boy, who developed an adhesive small bowel obstruction six weeks after abdominal surgery.

Open Access Case Study

Cutaneous Mucormycosis Following Trauma at the Surgical Site: A Rare Case

B. C. Vidyavathi, Rashmi P. Mahale, M. Krishna Karthik

International Journal of Medical and Pharmaceutical Case Reports, Page 1-4
DOI: 10.9734/IJMPCR/2018/41434

Mucormycosis is a highly aggressive fungal infection caused by Zygomycetes, belonging to the subphylum Mucormycotina in the order Mucorales. This infection commonly presents an aggressive and rapid course and typically affects immunocompromised patients. Mucormycosis can manifest in different clinical patterns and locations. Although the correct diagnosis is often difficult, early identification is essential for patient survival. Several clinical forms of mucormycosis are recognised. Cutaneous mucormycosis is less common than other clinical forms, but potentially lethal if treatment is not rapid. Tissue examination by histopathology and culture confirms the fungal infection. Standard treatment includes antifungal therapies associated with surgical debridement. We report a case of postoperative cutaneous mucormycosis followed by trauma with lethal outcome.